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Loss of GCNT2/I-branched glycans enhances melanoma growth and survival

Cancer cells often display altered cell-surface glycans compared to their nontransformed counterparts. However, functional contributions of glycans to cancer initiation and progression remain poorly understood. Here, from expression-based analyses across cancer lineages, we found that melanomas exhi...

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Detalles Bibliográficos
Autores principales: Sweeney, Jenna Geddes, Liang, Jennifer, Antonopoulos, Aristotelis, Giovannone, Nicholas, Kang, Shuli, Mondala, Tony S., Head, Steven R., King, Sandra L., Tani, Yoshihiko, Brackett, Danielle, Dell, Anne, Murphy, George F., Haslam, Stuart M., Widlund, Hans R., Dimitroff, Charles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105653/
https://www.ncbi.nlm.nih.gov/pubmed/30135430
http://dx.doi.org/10.1038/s41467-018-05795-0