Bioengineering of bacterial pathogens for noninvasive imaging and in vivo evaluation of therapeutics

Critical bacterial pathogens of public health and biodefense concerns were engineered to constitutively express Escherichia coli enzyme thymidine kinase (TK) that allows for noninvasive nuclear imaging via phosphorylation and entrapment of radiolabeled nucleoside analog 1-(2′deoxy-2′-fluoro-β-D-arab...

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Detalles Bibliográficos
Autores principales: Rajamani, Sathish, Kuszpit, Kyle, Scarff, Jennifer M., Lundh, Linnea, Khan, Maisha, Brown, Jennifer, Stafford, Robert, Cazares, Lisa H., Panchal, Rekha G., Bocan, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105664/
https://www.ncbi.nlm.nih.gov/pubmed/30135466
http://dx.doi.org/10.1038/s41598-018-30806-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105664/
https://www.ncbi.nlm.nih.gov/pubmed/30135466
http://dx.doi.org/10.1038/s41598-018-30806-x

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