Genomic patterns of progression in smoldering multiple myeloma

We analyzed whole genomes of unique paired samples from smoldering multiple myeloma (SMM) patients progressing to multiple myeloma (MM). We report that the genomic landscape, including mutational profile and structural rearrangements at the smoldering stage is very similar to MM. Paired sample analy...

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Detalles Bibliográficos
Autores principales: Bolli, Niccolò, Maura, Francesco, Minvielle, Stephane, Gloznik, Dominik, Szalat, Raphael, Fullam, Anthony, Martincorena, Inigo, Dawson, Kevin J., Samur, Mehmet Kemal, Zamora, Jorge, Tarpey, Patrick, Davies, Helen, Fulciniti, Mariateresa, Shammas, Masood A., Tai, Yu Tzu, Magrangeas, Florence, Moreau, Philippe, Corradini, Paolo, Anderson, Kenneth, Alexandrov, Ludmil, Wedge, David C., Avet-Loiseau, Herve, Campbell, Peter, Munshi, Nikhil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105687/
https://www.ncbi.nlm.nih.gov/pubmed/30135448
http://dx.doi.org/10.1038/s41467-018-05058-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105687/
https://www.ncbi.nlm.nih.gov/pubmed/30135448
http://dx.doi.org/10.1038/s41467-018-05058-y

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