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Genomic patterns of progression in smoldering multiple myeloma
We analyzed whole genomes of unique paired samples from smoldering multiple myeloma (SMM) patients progressing to multiple myeloma (MM). We report that the genomic landscape, including mutational profile and structural rearrangements at the smoldering stage is very similar to MM. Paired sample analy...
Autores principales: | Bolli, Niccolò, Maura, Francesco, Minvielle, Stephane, Gloznik, Dominik, Szalat, Raphael, Fullam, Anthony, Martincorena, Inigo, Dawson, Kevin J., Samur, Mehmet Kemal, Zamora, Jorge, Tarpey, Patrick, Davies, Helen, Fulciniti, Mariateresa, Shammas, Masood A., Tai, Yu Tzu, Magrangeas, Florence, Moreau, Philippe, Corradini, Paolo, Anderson, Kenneth, Alexandrov, Ludmil, Wedge, David C., Avet-Loiseau, Herve, Campbell, Peter, Munshi, Nikhil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105687/ https://www.ncbi.nlm.nih.gov/pubmed/30135448 http://dx.doi.org/10.1038/s41467-018-05058-y |
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