Real-Time Signaling Assays Demonstrate Somatostatin Agonist Bias for Ion Channel Regulation in Somatotroph Tumor Cells

Acromegaly is a neuroendocrine disorder caused by excess secretion of GH by somatotroph tumor cells. It is often treated with somatostatin receptor (SSTR) 2 agonists, which suppress GH secretion. SOM230 is a somatostatin analogue that targets multiple SSTRs and was recently approved for patients wit...

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Detalles Bibliográficos
Autores principales: Rodriguez, Melissa, Frost, Jeffrey A, Schonbrunn, Agnes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106105/
https://www.ncbi.nlm.nih.gov/pubmed/30151433
http://dx.doi.org/10.1210/js.2018-00115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106105/
https://www.ncbi.nlm.nih.gov/pubmed/30151433
http://dx.doi.org/10.1210/js.2018-00115

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