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Tolerability, pharmacokinetics, and pharmacodynamics of mirogabalin in healthy subjects: Results from phase 1 studies

Three phase 1 pharmacokinetic (PK)/pharmacodynamics (PD) studies were conducted in healthy men and women to further characterize the safety, tolerability, and PK/PD of mirogabalin administration with or without food and to guide the dose selection and regimen for phase 2 and 3 clinical development....

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Detalles Bibliográficos
Autores principales: Brown, Karen, Mendell, Jeanne, Ohwada, Shoichi, Hsu, Ching, He, Ling, Warren, Vance, Dishy, Victor, Zahir, Hamim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106189/
https://www.ncbi.nlm.nih.gov/pubmed/30151212
http://dx.doi.org/10.1002/prp2.418