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Correlation of Severity of Human Tick-Borne Encephalitis Virus Disease and Pathogenicity in Mice

We compared 2 tick-borne encephalitis virus strains isolated from 2 different foci that cause different symptoms in tick-borne encephalitis patients, from neurologic to mild gastrointestinal symptoms. We compared neuroinvasiveness, neurovirulence, and proinflammatory cytokine response in mice and fo...

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Detalles Bibliográficos
Autores principales: Kurhade, Chaitanya, Schreier, Sarah, Lee, Yi-Ping, Zegenhagen, Loreen, Hjertqvist, Marika, Dobler, Gerhard, Kröger, Andrea, Överby, Anna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106420/
https://www.ncbi.nlm.nih.gov/pubmed/30124404
http://dx.doi.org/10.3201/eid2409.171825