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Early Trypanosoma cruzi Infection Triggers mTORC1-Mediated Respiration Increase and Mitochondrial Biogenesis in Human Primary Cardiomyocytes

Chagasic chronic cardiomyopathy is one of the most frequent and severe manifestations of Chagas disease, caused by the parasite Trypanosoma cruzi. The pathogenic and biochemical mechanisms responsible for cardiac lesions remain not completely understood, although it is clear that hypertrophy and sub...

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Detalles Bibliográficos
Autores principales: Libisch, M. Gabriela, Faral-Tello, Paula, Garg, Nisha J., Radi, Rafael, Piacenza, Lucía, Robello, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106620/
https://www.ncbi.nlm.nih.gov/pubmed/30166980
http://dx.doi.org/10.3389/fmicb.2018.01889