Multiple Molecular Mechanisms Rescue mtDNA Disease in C. elegans

Genetic instability of the mitochondrial genome (mtDNA) plays an important role in human aging and disease. Thus far, it has proven difficult to develop successful treatment strategies for diseases that are caused by mtDNA instability. To address this issue, we developed a model of mtDNA disease in...

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Detalles Bibliográficos
Autores principales: Haroon, Suraiya, Li, Annie, Weinert, Jaye L., Fritsch, Clark, Ericson, Nolan G., Alexander-Floyd, Jasmine, Braeckman, Bart P., Haynes, Cole M., Bielas, Jason H., Gidalevitz, Tali, Vermulst, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106782/
https://www.ncbi.nlm.nih.gov/pubmed/29562168
http://dx.doi.org/10.1016/j.celrep.2018.02.099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106782/
https://www.ncbi.nlm.nih.gov/pubmed/29562168
http://dx.doi.org/10.1016/j.celrep.2018.02.099

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