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Multiple Molecular Mechanisms Rescue mtDNA Disease in C. elegans
Genetic instability of the mitochondrial genome (mtDNA) plays an important role in human aging and disease. Thus far, it has proven difficult to develop successful treatment strategies for diseases that are caused by mtDNA instability. To address this issue, we developed a model of mtDNA disease in...
Autores principales: | Haroon, Suraiya, Li, Annie, Weinert, Jaye L., Fritsch, Clark, Ericson, Nolan G., Alexander-Floyd, Jasmine, Braeckman, Bart P., Haynes, Cole M., Bielas, Jason H., Gidalevitz, Tali, Vermulst, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106782/ https://www.ncbi.nlm.nih.gov/pubmed/29562168 http://dx.doi.org/10.1016/j.celrep.2018.02.099 |
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