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CFTR is required for the migration of primordial germ cells during zebrafish early embryogenesis

Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene affect fertility in both sexes. However, the involvement of CFTR in regulating germ cell development remains largely unknown. Here, we used zebrafish model to investigate the role of CFTR in primordial germ cells (PGCs)...

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Detalles Bibliográficos
Autores principales: Liao, Huijuan, Chen, Yan, Li, Yulong, Xue, Shaolong, Liu, Mingfeng, Lin, Ziyuan, Liu, Yanyan, Chan, Hsiao Chang, Zhang, Xiaohu, Sun, Huaqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106808/
https://www.ncbi.nlm.nih.gov/pubmed/29930176
http://dx.doi.org/10.1530/REP-17-0681