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Murine host response to Neisseria gonorrhoeae upper genital tract infection reveals a common transcriptional signature, plus distinct inflammatory responses that vary between reproductive cycle phases

BACKGROUND: The emergence of fully antimicrobial resistant Neisseria gonorrhoeae has led global public health agencies to identify a critical need for next generation anti-gonococcal pharmaceuticals. The development and success of these compounds will rely upon valid pre-clinical models of gonorrhoe...

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Detalles Bibliográficos
Autores principales: Francis, Ian P., Islam, Epshita A., Gower, Adam C., Shaik-Dasthagirisaheb, Yazdani B., Gray-Owen, Scott D., Wetzler, Lee M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106831/
https://www.ncbi.nlm.nih.gov/pubmed/30134832
http://dx.doi.org/10.1186/s12864-018-5000-7