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Misidentification of runs of homozygosity islands in cattle caused by interference with copy number variation or large intermarker distances
BACKGROUND: Runs of homozygosity (ROH) islands are stretches of homozygous sequence in the genome of a large proportion of individuals in a population. Algorithms for the detection of ROH depend on the similarity of haplotypes. Coverage gaps and copy number variants (CNV) may result in incorrect ide...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106898/ https://www.ncbi.nlm.nih.gov/pubmed/30134820 http://dx.doi.org/10.1186/s12711-018-0414-x |