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A novel mutation of MSX1 in oligodontia inhibits odontogenesis of dental pulp stem cells via the ERK pathway

BACKGROUND: Tooth agenesis, one of the most common developmental anomalies, can affect the function and esthetics of patients. The aim of the present study was to identify genetic clues for familial tooth agenesis and explore the underlying mechanisms, focusing on the role of human dental pulp stem...

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Detalles Bibliográficos
Autores principales: Xin, Tianyi, Zhang, Ting, Li, Qian, Yu, Tingting, Zhu, Yunyan, Yang, Ruili, Zhou, Yanheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106924/
https://www.ncbi.nlm.nih.gov/pubmed/30134957
http://dx.doi.org/10.1186/s13287-018-0965-3