Cargando…

The Subcellular Distribution of Ryanodine Receptors and L-Type Ca(2+) Channels Modulates Ca(2+)-Transient Properties and Spontaneous Ca(2+)-Release Events in Atrial Cardiomyocytes

Spontaneous Ca(2+)-release events (SCaEs) from the sarcoplasmic reticulum play crucial roles in the initiation of cardiac arrhythmias by promoting triggered activity. However, the subcellular determinants of these SCaEs remain incompletely understood. Structural differences between atrial and ventri...

Descripción completa

Detalles Bibliográficos
Autores principales: Sutanto, Henry, van Sloun, Bart, Schönleitner, Patrick, van Zandvoort, Marc A. M. J., Antoons, Gudrun, Heijman, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107030/
https://www.ncbi.nlm.nih.gov/pubmed/30166973
http://dx.doi.org/10.3389/fphys.2018.01108