Cargando…
The Subcellular Distribution of Ryanodine Receptors and L-Type Ca(2+) Channels Modulates Ca(2+)-Transient Properties and Spontaneous Ca(2+)-Release Events in Atrial Cardiomyocytes
Spontaneous Ca(2+)-release events (SCaEs) from the sarcoplasmic reticulum play crucial roles in the initiation of cardiac arrhythmias by promoting triggered activity. However, the subcellular determinants of these SCaEs remain incompletely understood. Structural differences between atrial and ventri...
Autores principales: | Sutanto, Henry, van Sloun, Bart, Schönleitner, Patrick, van Zandvoort, Marc A. M. J., Antoons, Gudrun, Heijman, Jordi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107030/ https://www.ncbi.nlm.nih.gov/pubmed/30166973 http://dx.doi.org/10.3389/fphys.2018.01108 |
Ejemplares similares
-
Subcellular Ca(2+) signaling in the heart: the role of ryanodine receptor sensitivity
por: Prosser, Benjamin L., et al.
Publicado: (2010) -
Detection of Ca(2+) transients near ryanodine receptors by targeting fluorescent Ca(2+) sensors to the triad
por: Sanchez, Colline, et al.
Publicado: (2021) -
Cardiomyocyte Na(+) and Ca(2+) mishandling drives vicious cycle involving CaMKII, ROS, and ryanodine receptors
por: Hegyi, Bence, et al.
Publicado: (2021) -
Coupling of SK channels, L-type Ca(2+) channels, and ryanodine receptors in cardiomyocytes
por: Zhang, Xiao-Dong, et al.
Publicado: (2018) -
Molecular Basis of Ca(2)+ Activation of the Mouse Cardiac Ca(2)+ Release Channel (Ryanodine Receptor)
por: Li, Pin, et al.
Publicado: (2001)