Cargando…

Relative Evolutionary Rates in Proteins Are Largely Insensitive to the Substitution Model

The relative evolutionary rates at individual sites in proteins are informative measures of conservation or adaptation. Often used as evolutionarily aware conservation scores, relative rates reveal key functional or strongly selected residues. Estimating rates in a phylogenetic context requires spec...

Descripción completa

Detalles Bibliográficos
Autores principales: Spielman, Stephanie J, Kosakovsky Pond, Sergei L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107055/
https://www.ncbi.nlm.nih.gov/pubmed/29924340
http://dx.doi.org/10.1093/molbev/msy127