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Relative Evolutionary Rates in Proteins Are Largely Insensitive to the Substitution Model
The relative evolutionary rates at individual sites in proteins are informative measures of conservation or adaptation. Often used as evolutionarily aware conservation scores, relative rates reveal key functional or strongly selected residues. Estimating rates in a phylogenetic context requires spec...
Autores principales: | Spielman, Stephanie J, Kosakovsky Pond, Sergei L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107055/ https://www.ncbi.nlm.nih.gov/pubmed/29924340 http://dx.doi.org/10.1093/molbev/msy127 |
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