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Toll-Like Receptor Evolution in Birds: Gene Duplication, Pseudogenization, and Diversifying Selection
Toll-like receptors (TLRs) are key sensor molecules in vertebrates triggering initial phases of immune responses to pathogens. The avian TLR family typically consists of ten receptors, each adapted to distinct ligands. To understand the complex evolutionary history of each avian TLR, we analyzed all...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107061/ https://www.ncbi.nlm.nih.gov/pubmed/29893911 http://dx.doi.org/10.1093/molbev/msy119 |