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Toll-Like Receptor Evolution in Birds: Gene Duplication, Pseudogenization, and Diversifying Selection

Toll-like receptors (TLRs) are key sensor molecules in vertebrates triggering initial phases of immune responses to pathogens. The avian TLR family typically consists of ten receptors, each adapted to distinct ligands. To understand the complex evolutionary history of each avian TLR, we analyzed all...

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Detalles Bibliográficos
Autores principales: Velová, Hana, Gutowska-Ding, Maria W, Burt, David W, Vinkler, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107061/
https://www.ncbi.nlm.nih.gov/pubmed/29893911
http://dx.doi.org/10.1093/molbev/msy119