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Effects of metal ions on caspase-1 activation and interleukin-1β release in murine bone marrow-derived macrophages
Ions released from metal implants have been associated with adverse tissue reactions and are therefore a major concern. Studies with macrophages have shown that cobalt, chromium, and nickel ions can activate the NLRP3 inflammasome, a multiprotein complex responsible for the activation of caspase-1 (...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107125/ https://www.ncbi.nlm.nih.gov/pubmed/30138321 http://dx.doi.org/10.1371/journal.pone.0199936 |