Investigation of interactions between TLR2, MyD88 and TIRAP by bioluminescence resonance energy transfer is hampered by artefacts of protein overexpression

Toll like receptors (TLRs) are important pattern recognition receptors that can detect pathogen and danger associated molecular patterns to initiate an innate immune response. TLR1 and 2 heterodimerize at the plasma membrane upon binding to triacylated lipopeptides from bacterial cell walls, or to t...

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Detalles Bibliográficos
Autores principales: Sampaio, Natália G., Kocan, Martina, Schofield, Louis, Pfleger, Kevin D. G., Eriksson, Emily M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107161/
https://www.ncbi.nlm.nih.gov/pubmed/30138457
http://dx.doi.org/10.1371/journal.pone.0202408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107161/
https://www.ncbi.nlm.nih.gov/pubmed/30138457
http://dx.doi.org/10.1371/journal.pone.0202408

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