The activation of lactate dehydrogenase induced by mTOR drives neoplastic change in breast epithelial cells

mTOR kinase and the A isoform of lactate dehydrogenase (LDH-A) are key players controlling the metabolic characteristics of cancer cells. By using cultured human breast cells as a “metabolic tumor” model, we attempted to explore the correlation between these two factors. “Metabolic tumors” are defin...

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Detalles Bibliográficos
Autores principales: Manerba, Marcella, Di Ianni, Lorenza, Govoni, Marzia, Comparone, Antonietta, Di Stefano, Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107208/
https://www.ncbi.nlm.nih.gov/pubmed/30138330
http://dx.doi.org/10.1371/journal.pone.0202588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107208/
https://www.ncbi.nlm.nih.gov/pubmed/30138330
http://dx.doi.org/10.1371/journal.pone.0202588

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