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The activation of lactate dehydrogenase induced by mTOR drives neoplastic change in breast epithelial cells
mTOR kinase and the A isoform of lactate dehydrogenase (LDH-A) are key players controlling the metabolic characteristics of cancer cells. By using cultured human breast cells as a “metabolic tumor” model, we attempted to explore the correlation between these two factors. “Metabolic tumors” are defin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107208/ https://www.ncbi.nlm.nih.gov/pubmed/30138330 http://dx.doi.org/10.1371/journal.pone.0202588 |