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An improved method for the isolation and identification of unknown proteins that bind to known DNA sequences by affinity capture and mass spectrometry
Transcription of a gene can be regulated at many different levels. One such fundamental level is interaction between protein and DNA. Protein(s) binds to distinct sites on the DNA, which activate, enhance or repress transcription. Despite being such an important process, very few tools exist to iden...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107227/ https://www.ncbi.nlm.nih.gov/pubmed/30138440 http://dx.doi.org/10.1371/journal.pone.0202602 |