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The cat as a naturally occurring model of renal interstitial fibrosis: Characterisation of primary feline proximal tubular epithelial cells and comparative pro-fibrotic effects of TGF-β1

Chronic kidney disease (CKD) is common in both geriatric cats and aging humans, and is pathologically characterised by chronic tubulointerstitial inflammation and fibrosis in both species. Cats with CKD may represent a spontaneously occurring, non-rodent animal model of human disease, however little...

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Detalles Bibliográficos
Autores principales: Lawson, Jack S., Liu, Hui-Hsuan, Syme, Harriet M., Purcell, Robert, Wheeler-Jones, Caroline P. D., Elliott, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107233/
https://www.ncbi.nlm.nih.gov/pubmed/30138414
http://dx.doi.org/10.1371/journal.pone.0202577