Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap

Recent studies suggest that some monoclonal antibodies (mAbs) specific for ebolavirus glycoprotein (GP) can protect experimental animals against infections. Most mAbs isolated from ebolavirus survivors appeared to target the glycan cap or the stalk region of the viral GP, which is the envelope prote...

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Detalles Bibliográficos
Autores principales: Ilinykh, Philipp A., Santos, Rodrigo I., Gunn, Bronwyn M., Kuzmina, Natalia A., Shen, Xiaoli, Huang, Kai, Gilchuk, Pavlo, Flyak, Andrew I., Younan, Patrick, Alter, Galit, Crowe, James E., Bukreyev, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107261/
https://www.ncbi.nlm.nih.gov/pubmed/30138408
http://dx.doi.org/10.1371/journal.ppat.1007204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107261/
https://www.ncbi.nlm.nih.gov/pubmed/30138408
http://dx.doi.org/10.1371/journal.ppat.1007204

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