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Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap
Recent studies suggest that some monoclonal antibodies (mAbs) specific for ebolavirus glycoprotein (GP) can protect experimental animals against infections. Most mAbs isolated from ebolavirus survivors appeared to target the glycan cap or the stalk region of the viral GP, which is the envelope prote...
Autores principales: | Ilinykh, Philipp A., Santos, Rodrigo I., Gunn, Bronwyn M., Kuzmina, Natalia A., Shen, Xiaoli, Huang, Kai, Gilchuk, Pavlo, Flyak, Andrew I., Younan, Patrick, Alter, Galit, Crowe, James E., Bukreyev, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107261/ https://www.ncbi.nlm.nih.gov/pubmed/30138408 http://dx.doi.org/10.1371/journal.ppat.1007204 |
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