Distinct substrate specificity and physicochemical characterization of native human hepatic thymidine phosphorylase

Thymidine phosphorylase (TP; EC 2.4.2.4) is involved regulation of intra- or extracellular thymidine concentration, angiogenesis, cancer chemotherapy, radiotherapy, as well as tumor imaging. Although the liver is main site of pyrimidine metabolism and contains high levels of TP, nonetheless, purific...

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Detalles Bibliográficos
Autores principales: Oh, Taesung, el Kouni, Mahmoud H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107277/
https://www.ncbi.nlm.nih.gov/pubmed/30138393
http://dx.doi.org/10.1371/journal.pone.0202826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107277/
https://www.ncbi.nlm.nih.gov/pubmed/30138393
http://dx.doi.org/10.1371/journal.pone.0202826

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