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Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2

The trimeric SARS coronavirus (SARS-CoV) surface spike (S) glycoprotein consisting of three S1-S2 heterodimers binds the cellular receptor angiotensin-converting enzyme 2 (ACE2) and mediates fusion of the viral and cellular membranes through a pre- to postfusion conformation transition. Here, we rep...

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Detalles Bibliográficos
Autores principales: Song, Wenfei, Gui, Miao, Wang, Xinquan, Xiang, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107290/
https://www.ncbi.nlm.nih.gov/pubmed/30102747
http://dx.doi.org/10.1371/journal.ppat.1007236