A genome-wide association study identifies a susceptibility locus for biliary atresia on 2p16.1 within the gene EFEMP1

Biliary atresia (BA) is a rare pediatric cholangiopathy characterized by fibrosclerosing obliteration of the extrahepatic bile ducts, leading to cholestasis, fibrosis, cirrhosis, and eventual liver failure. The etiology of BA remains unknown, although environmental, inflammatory, infectious, and gen...

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Detalles Bibliográficos
Autores principales: Chen, Ying, Gilbert, Melissa A., Grochowski, Christopher M., McEldrew, Deborah, Llewellyn, Jessica, Waisbourd-Zinman, Orith, Hakonarson, Hakon, Bailey-Wilson, Joan E., Russo, Pierre, Wells, Rebecca G., Loomes, Kathleen M., Spinner, Nancy B., Devoto, Marcella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107291/
https://www.ncbi.nlm.nih.gov/pubmed/30102696
http://dx.doi.org/10.1371/journal.pgen.1007532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107291/
https://www.ncbi.nlm.nih.gov/pubmed/30102696
http://dx.doi.org/10.1371/journal.pgen.1007532

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