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Restoration of vision after de novo genesis of rod photoreceptors in mammalian retinas

In zebrafish, Müller glial cells (MGs) are a source of retinal stem cells that can replenish damaged retinal neurons and restore vision(1). In mammals, however, MGs lack regenerative capability as they do not spontaneously re-enter the cell cycle to generate a population of stem/progenitor cells tha...

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Detalles Bibliográficos
Autores principales: Yao, Kai, Qiu, Suo, Wang, Yanbin V., Park, Silvia J.H., Mohns, Ethan J., Mehta, Bhupesh, Liu, Xinran, Chang, Bo, Zenisek, David, Crair, Michael C., Demb, Jonathan B., Chen, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107416/
https://www.ncbi.nlm.nih.gov/pubmed/30111842
http://dx.doi.org/10.1038/s41586-018-0425-3