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Identification of new type I interferon-stimulated genes and investigation of their involvement in IFN-β activation

Virus infection induces the production of type I interferons (IFNs). IFNs bind to their heterodimeric receptors to initiate downstream cascade of signaling, leading to the up-regulation of interferon-stimulated genes (ISGs). ISGs play very important roles in innate immunity through a variety of mech...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaolin, Yang, Wei, Wang, Xinlu, Zhang, Xuyuan, Tian, Huabin, Deng, Hongyu, Zhang, Liguo, Gao, Guangxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107486/
https://www.ncbi.nlm.nih.gov/pubmed/29427062
http://dx.doi.org/10.1007/s13238-018-0511-1