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Identification of new type I interferon-stimulated genes and investigation of their involvement in IFN-β activation
Virus infection induces the production of type I interferons (IFNs). IFNs bind to their heterodimeric receptors to initiate downstream cascade of signaling, leading to the up-regulation of interferon-stimulated genes (ISGs). ISGs play very important roles in innate immunity through a variety of mech...
Autores principales: | Zhang, Xiaolin, Yang, Wei, Wang, Xinlu, Zhang, Xuyuan, Tian, Huabin, Deng, Hongyu, Zhang, Liguo, Gao, Guangxia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107486/ https://www.ncbi.nlm.nih.gov/pubmed/29427062 http://dx.doi.org/10.1007/s13238-018-0511-1 |
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