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Tumour cell invasiveness and response to chemotherapeutics in adipocyte invested 3D engineered anisotropic collagen scaffolds

Breast cancers are highly heterogeneous and their metastatic potential and response to therapeutic drugs is difficult to predict. A tool that could accurately gauge tumour invasiveness and drug response would provide a valuable addition to the oncologist’s arsenal. We have developed a 3-dimensional...

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Detalles Bibliográficos
Autores principales: Hume, Robert D., Pensa, Sara, Brown, Elizabeth J., Kreuzaler, Peter A., Hitchcock, Jessica, Husmann, Anke, Campbell, Jonathan J., Lloyd-Thomas, Annabel O., Cameron, Ruth E., Watson, Christine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107500/
https://www.ncbi.nlm.nih.gov/pubmed/30139956
http://dx.doi.org/10.1038/s41598-018-30107-3