Factor H binding proteins protect division septa on encapsulated Streptococcus pneumoniae against complement C3b deposition and amplification

Streptococcus pneumoniae evades C3-mediated opsonization and effector functions by expressing an immuno-protective polysaccharide capsule and Factor H (FH)-binding proteins. Here we use super-resolution microscopy, mutants and functional analysis to show how these two defense mechanisms are function...

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Detalles Bibliográficos
Autores principales: Pathak, Anuj, Bergstrand, Jan, Sender, Vicky, Spelmink, Laura, Aschtgen, Marie-Stephanie, Muschiol, Sandra, Widengren, Jerker, Henriques-Normark, Birgitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107515/
https://www.ncbi.nlm.nih.gov/pubmed/30139996
http://dx.doi.org/10.1038/s41467-018-05494-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107515/
https://www.ncbi.nlm.nih.gov/pubmed/30139996
http://dx.doi.org/10.1038/s41467-018-05494-w

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