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Factor H binding proteins protect division septa on encapsulated Streptococcus pneumoniae against complement C3b deposition and amplification

Streptococcus pneumoniae evades C3-mediated opsonization and effector functions by expressing an immuno-protective polysaccharide capsule and Factor H (FH)-binding proteins. Here we use super-resolution microscopy, mutants and functional analysis to show how these two defense mechanisms are function...

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Detalles Bibliográficos
Autores principales:	Pathak, Anuj, Bergstrand, Jan, Sender, Vicky, Spelmink, Laura, Aschtgen, Marie-Stephanie, Muschiol, Sandra, Widengren, Jerker, Henriques-Normark, Birgitta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107515/ https://www.ncbi.nlm.nih.gov/pubmed/30139996 http://dx.doi.org/10.1038/s41467-018-05494-w

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