Identification and characterization of aspartyl-tRNA synthetase inhibitors against Mycobacterium tuberculosis by an integrated whole-cell target-based approach

Mycobacterium tuberculosis, the causative agent of tuberculosis, has surpassed HIV as the leading cause of death due to an infectious disease worldwide, being responsible for more than 1.5 million deaths in low-income countries. In response to a pandemic threat by drug resistant strains, the tubercu...

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Detalles Bibliográficos
Autores principales: Soto, Ramón, Perez-Herran, Esther, Rodriguez, Beatriz, Duma, Bogdan M., Cacho-Izquierdo, Monica, Mendoza-Losana, Alfonso, Lelievre, Joel, Aguirre, David Barros, Ballell, Lluis, Cox, Liam R., Alderwick, Luke J., Besra, Gurdyal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107548/
https://www.ncbi.nlm.nih.gov/pubmed/30140040
http://dx.doi.org/10.1038/s41598-018-31157-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107548/
https://www.ncbi.nlm.nih.gov/pubmed/30140040
http://dx.doi.org/10.1038/s41598-018-31157-3

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