MicroRNA 375 modulates hyperglycemia-induced enteric glial cell apoptosis and Diabetes-induced gastrointestinal dysfunction by targeting Pdk1 and repressing PI3K/Akt pathway

Diabetic neuropathy can damage systemic nervous system, including alteration of enteric nervous system and subsequent gastrointestinal dysfunction. The effect of diabetes on enteric glia cell (EGC) is not clear. We investigated the effect of diabetes and hyperglycemia on EGC, and the role of microRN...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Liu, Gongxiang, He, Fuqian, Zhang, Li, Yang, Kun, Yu, Huan, Zhou, Jinqiu, Gan, Huatian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107553/
https://www.ncbi.nlm.nih.gov/pubmed/30140011
http://dx.doi.org/10.1038/s41598-018-30714-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107553/
https://www.ncbi.nlm.nih.gov/pubmed/30140011
http://dx.doi.org/10.1038/s41598-018-30714-0

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