AMPK contributes to autophagosome maturation and lysosomal fusion

AMP-activated protein kinase (AMPK) regulates autophagy initiation when intracellular ATP level decreases. However, the role of AMPK during autophagosome maturation is not fully understood. Here, we report that AMPK contributes to efficient autophagosome maturation and lysosomal fusion. Using CRISPR...

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Detalles Bibliográficos
Autores principales: Jang, Minsu, Park, Rackhyun, Kim, Hyunju, Namkoong, Sim, Jo, Daum, Huh, Yang Hoon, Jang, Ik-Soon, Lee, Jin I., Park, Junsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107659/
https://www.ncbi.nlm.nih.gov/pubmed/30140075
http://dx.doi.org/10.1038/s41598-018-30977-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107659/
https://www.ncbi.nlm.nih.gov/pubmed/30140075
http://dx.doi.org/10.1038/s41598-018-30977-7

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