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Toll-like Receptor 4 Pathway Polymorphisms Interact with Pollution to Influence Asthma Diagnosis and Severity

Asthma is a common chronic lung disease, the incidence and severity of which may be influenced by gene-environment interactions. Our objective was to examine associations between single nucleotide polymorphisms (SNPs) and combinations of SNPs in the toll-like receptor 4 (TLR4) pathway, residential d...

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Detalles Bibliográficos
Autores principales: Schurman, Shepherd H., Bravo, Mercedes A., Innes, Cynthia L., Jackson, W. Braxton, McGrath, John A., Miranda, Marie Lynn, Garantziotis, Stavros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107668/
https://www.ncbi.nlm.nih.gov/pubmed/30140039
http://dx.doi.org/10.1038/s41598-018-30865-0