Circulating H3Cit is elevated in a human model of endotoxemia and can be detected bound to microvesicles

Early diagnosis of sepsis is crucial since prompt interventions decrease mortality. Citrullinated histone H3 (H3Cit), released from neutrophil extracellular traps (NETs) upon binding of platelets to neutrophils following endotoxin stimulation, has recently been proposed a promising blood biomarker i...

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Detalles Bibliográficos
Autores principales: Paues Göranson, Sofie, Thålin, Charlotte, Lundström, Annika, Hållström, Lars, Lasselin, Julie, Wallén, Håkan, Soop, Anne, Mobarrez, Fariborz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107669/
https://www.ncbi.nlm.nih.gov/pubmed/30140006
http://dx.doi.org/10.1038/s41598-018-31013-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107669/
https://www.ncbi.nlm.nih.gov/pubmed/30140006
http://dx.doi.org/10.1038/s41598-018-31013-4

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