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Use of a Caco-2 permeability assay to evaluate the effects of several Kampo medicines on the drug transporter P-glycoprotein

In modern medical care in which Kampo and Western drugs are often combined, it is extremely important to clarify drug–drug interaction (DDI) to ensure safety and efficacy. However, there is little evidence of DDI in Kampo medicines. Therefore, as part of our studies to clarify the DDI risk for Kampo...

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Detalles Bibliográficos
Autores principales: Matsumoto, Takashi, Kaifuchi, Noriko, Mizuhara, Yasuharu, Warabi, Eiji, Watanabe, Junko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107777/
https://www.ncbi.nlm.nih.gov/pubmed/29797179
http://dx.doi.org/10.1007/s11418-018-1222-x