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Quantifying the Intrinsic Conformation Energy Landscape Topography of Proteins with Large-Scale Open–Closed Transition
[Image: see text] Large-scale conformational changes of proteins, including the open–closed transitions, are crucial for a variety of protein functions. These open–closed transitions are often associated with ligand binding. However, the understandings of the underlying mechanisms of the conformatio...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107866/ https://www.ncbi.nlm.nih.gov/pubmed/30159398 http://dx.doi.org/10.1021/acscentsci.8b00274 |