Dysregulated transcriptional networks in KMT2A- and MLLT10-rearranged T-ALL

For children and young adults with T-lineage acute lymphoblastic leukemia (T-ALL), event free survival following relapse is < 10%. We recently showed that rearrangements of the mixed lineage leukemia gene (KMT2A-R) are associated with induction failure and an inferior survival in T-ALL. Because t...

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Detalles Bibliográficos
Autores principales: Kang, Huining, Sharma, Nitesh D., Nickl, Christian K., Devidas, Meenakshi, Loh, Mignon L., Hunger, Stephen P., Dunsmore, Kimberly P., Winter, Stuart S., Matlawska-Wasowska, Ksenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107954/
https://www.ncbi.nlm.nih.gov/pubmed/30159143
http://dx.doi.org/10.1186/s40364-018-0141-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107954/
https://www.ncbi.nlm.nih.gov/pubmed/30159143
http://dx.doi.org/10.1186/s40364-018-0141-z

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