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A robust Pax7EGFP mouse that enables the visualization of dynamic behaviors of muscle stem cells

BACKGROUND: Pax7 is a transcription factor involved in the specification and maintenance of muscle stem cells (MuSCs). Upon injury, MuSCs leave their quiescent state, downregulate Pax7 and differentiate, contributing to skeletal muscle regeneration. In the majority of regeneration studies, MuSCs are...

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Detalles Bibliográficos
Autores principales: Tichy, Elisia D., Sidibe, David K., Greer, Christopher D., Oyster, Nicholas M., Rompolas, Panteleimon, Rosenthal, Nadia A., Blau, Helen M., Mourkioti, Foteini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107960/
https://www.ncbi.nlm.nih.gov/pubmed/30139374
http://dx.doi.org/10.1186/s13395-018-0169-7