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Nascent RNA sequencing analysis provides insights into enhancer-mediated gene regulation

BACKGROUND: Enhancers are distal cis-regulatory elements that control gene expression. Despite an increasing appreciation of the importance of enhancers in cellular function and disease, our knowledge of enhancer-regulated transcription is very limited. Nascent RNA sequencing technologies, such as g...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Zhao, Yue, Zhou, Xiaofan, Hiebert, Scott W., Liu, Qi, Shyr, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107967/
https://www.ncbi.nlm.nih.gov/pubmed/30139328
http://dx.doi.org/10.1186/s12864-018-5016-z