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Evaluating the safety, tolerability, pharmacokinetics and efficacy of clofazimine in cryptosporidiosis (CRYPTOFAZ): study protocol for a randomized controlled trial

BACKGROUND: Cryptosporidium infection and diarrhea (cryptosporidiosis) is a life-threatening infection in persons with HIV and also in children of 6–18 months of age in the developing world. To date, only nitazoxanide is licensed for treatment of cryptosporidiosis, and only in persons after the firs...

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Detalles Bibliográficos
Autores principales: Nachipo, Patrick, Hermann, David, Quinnan, Gerald, Gordon, Melita A., Van Voorhis, Wesley C., Iroh Tam, Pui-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108095/
https://www.ncbi.nlm.nih.gov/pubmed/30139372
http://dx.doi.org/10.1186/s13063-018-2846-6