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The roles of metallothioneins in carcinogenesis

Metallothioneins (MTs) are small cysteine-rich proteins that play important roles in metal homeostasis and protection against heavy metal toxicity, DNA damage, and oxidative stress. In humans, MTs have four main isoforms (MT1, MT2, MT3, and MT4) that are encoded by genes located on chromosome 16q13....

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Detalles Bibliográficos
Autores principales: Si, Manfei, Lang, Jinghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108115/
https://www.ncbi.nlm.nih.gov/pubmed/30139373
http://dx.doi.org/10.1186/s13045-018-0645-x