Cell permeable HMGB1-binding heptamer peptide ameliorates neurovascular complications associated with thrombolytic therapy in rats with transient ischemic stroke

BACKGROUND: Blood–brain barrier (BBB) breakdown and inflammatory responses are the major causes of tissue-type plasminogen activator (tPA)-induced hemorrhagic transformation (HT), while high-mobility group box 1 (HMGB1) exacerbates inflammatory damage to BBB during the process of brain ischemia/repe...

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Detalles Bibliográficos
Autores principales: Li, Miaodan, Chen, Shumin, Shi, Xue, Lyu, Chenfei, Zhang, Yongfang, Tan, Miaoqin, Wang, Chen, Zang, Nailiang, Liu, Xiaoxi, Hu, Yafang, Shen, Jiangang, Zhou, Liang, Gu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108117/
https://www.ncbi.nlm.nih.gov/pubmed/30139371
http://dx.doi.org/10.1186/s12974-018-1267-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108117/
https://www.ncbi.nlm.nih.gov/pubmed/30139371
http://dx.doi.org/10.1186/s12974-018-1267-5

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