Purification, characterization and immunogenicity assessment of glutaminase free L-asparaginase from Streptomyces brollosae NEAE-115

BACKGROUND: L-asparaginase is a potential therapeutic enzyme widely used in the chemotherapy protocols of pediatric and adult patients with acute lymphoblastic leukemia. However, its use has been limited by a high rate of hypersensitivity in the long-term used. Hence, there is a continuing need to s...

Descripción completa

Detalles Bibliográficos
Autores principales: El-Naggar, Noura El-Ahmady, Deraz, Sahar F., El-Ewasy, Sara M., Suddek, Ghada M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108126/
https://www.ncbi.nlm.nih.gov/pubmed/30139388
http://dx.doi.org/10.1186/s40360-018-0242-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108126/
https://www.ncbi.nlm.nih.gov/pubmed/30139388
http://dx.doi.org/10.1186/s40360-018-0242-1

Ejemplares similares